DNA TELOMERE TREATMENT

Anti-Aging Treatments at Regenerative Medicine LA

The twisted, double-stranded molecules of DNA are called chromosomes. Telomeres are sections of DNA at the end of each chromosome that serve as a cap to your genetic material.
DNA telomere treatment

Telomeres protect the genetic data and make it possible for cells to divide and holds secrets on how a person will age. Shorter telomeres imply a shorter life span for a cell. Telomeres keep chromosome ends from disentanglement and sticking to each other which otherwise would destroy the genetic information. Every time a cell replicates, its telomere will become shorter. When they get too short, they no longer divide and they become inactive or die. This process where the telomeres get shortened is associated with aging and cancer.

What is age-adjusted telomere length?

Age-adjusted telomere length is the best method to date to assess biological age using structural analysis of chromosomal change in the telomere. Annual evaluations of telomere length is an indicator of how rapidly one ages relative to a normal population. Our medical office can test your telomere length and provide treatment guided therapies shown to reduce telomere shortening. Therapies directed at slowing the loss of telomere length may slow aging and age-related diseases.

Shorter telomeres have been associated with metabolic abnormalities, obesity, and several degenerative diseases including cancer, dementia, and cardiovascular disease. In vitro studies have shown that telomeres are highly susceptible to oxidative stress, which will shorten telomere length and enhance cellular aging.

What are the lifestyle changes to be made to fight telomere shortening and aging?

Telomere shortening can be prevented with some lifestyle changes as an individual’s lifestyle affects health and lifespan, which directly affects telomere length. Minimizing associated risk factors that are linked to shortened telomere activity is recommended and include:

  • Maintain ideal weight: Shorter telomeres are triggered by excess weight and obesity. It also increases oxidative stress due to unregulated adipocytokine production, and production of oxidative agents in adipose tissue. As a result, the DNA is damaged, resulting in a shorter lifespan. Maintaining an ideal weight can help reduce the damage that can be caused.
  • A change in diet: Eating less is not the solution for a healthy diet, but calorie restriction is. Oxidative stress and DNA damage can be reduced by a controlled intake of calories, which can also reduce telomere shortening and slow down one’s aging.
  • Increase fiber intake: There is a positive correlation between long telomeres and a fiber-rich diet, and a negative correlation between protein-rich or fat diet and long telomeres. It is advised to take fiber rich food and reduce the consumption of protein and fat.
  • Give up active and passive smoking: Smoking never has any proven benefits. It increases telomere shortening and aging. It results in a considerable increase in oxidative stress. Giving up on active as well as passive smoking can slow down aging and helps limit telomeric DNA loss.
  • Relax and reduce stress: The antioxidant proteins produced by the body are blocked by the hormones released when you are stressed. Decreased antioxidants leads to a higher oxidative stress and induces telomere shortening.
  • Change sedentary lifestyle/increase physical activity: Sedentary lifestyle is the main reason behind fat accumulation and obesity. By changing one’s sedentary lifestyle to increased physical activity will help in keeping the oxidative stress levels down and prevents the shortening of telomeres.
  • Other suggestions to tackle shortening of telomere include:
    1. Correction of micronutrient deficiencies, especially vitamin D
    2. Correct insulin resistance
    3. Reducing oxidative stress

Studies have shown that telomere length is strongly associated with CVD risk, nutritional deficiencies (particularly antioxidants) and cancer and testing may be a useful biomarker for risk assessment. Annual telomere testing will be conducted to ensure we minimize the aging process.

What is the treatment for telomere shortening?

Peptide treatment has been proven by evidence-based studies to prevent shortening of telomeres thus assisting in the prevention of the aging process. Peptides are chains of amino acids linked together in a specific process to produce a protein. These protein or peptides are used by the body to facilitate cell-to-cell communication that allows the body to switch certain cell functions on or off.

Peptide therapy refers to the targeted use of peptides to produce a specific reaction in the body. Peptide therapy can be used to reduce the shortening of telomeres. It also helps:

  • To reduce weight by stimulating the breakdown of visceral fat
  • To reduce inflammation
  • To produce human growth hormone
  • As anti-aging therapies
  • To increase muscle mass

If you are suffering from an autoimmune disease, chronic inflammation, Lyme disease, or other chronic degenerative disease, visit Dr. Mark Ghalili at Regenerative Medicine, LA. You may be a candidate for and benefit from peptide therapy.

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Anti-Aging, Regenerative, & Integrative Medicine located in Los Angeles, CA
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