Stem Cell Information


 

Is Stem Cell Therapy For You?

 

What are Stem Cells and how can stem cells benefit me? 

Stem cells are undifferentiated cells with the ability to regenerate and convert into differentiated cells, producing various types of tissues.Adult mesenchymal stem cells (MSCs) can be found in a person’s blood, bone marrow, or adipose tissue (fat). Adipose fat tissue is an abundant source of stem cells. The best quality adipose cells are derived from the use of collagenase to breakdown the extracted fat. Autologous stem cells from a person’s own fat are easy to harvest safely under local anesthesia and on average produce quantities up to 2,500 times those seen in bone marrow. Bone marrow stem cell extractions are quite painful and carry a higher risk of infection. 


The higher the number of stem cells, the greater the probability of patient success. Once these adipose derived stem cells are given back into the patient through IV infusion or joint injection, they have the potential to repair damaged human tissue by influencing healing. Examples of these cells are bone, cartilage, nerves, fat, muscle, vessel walls, ligaments, and organ tissue. Stem cells’ ability to form bone and cartilage makes them potentially highly effective in the treatment of degenerative orthopedic conditions. Their ability to form new blood vessels and other tissues makes them suitable for modifying a large number of traumatic and degenerative conditions. In a recent study research showed that Stem Cells from adipose tissue, injected with platelet-rich plasma (PRP), could regenerate cartilage-like tissue in human osteoarthritis (OA) patients.1 Multiple case studies show significant improvement in patient pain and mobility levels after stem cell administration in the joints. Mesenchymal stem cells have resulted in pain and functional improvement in a number of preclinical and clinical trials. Importantly, recent limited case series evidence has shown regrowth of cartilage volume and disease modification following stem cell injections.2 A case series of 339 patients, reporting that of those patients requiring total knee replacement (69 %) only 6.9 % still required replacement surgery after stem cell therapy. Sixty percent of patients reported greater than 50% pain relief and 40% reported >75 % pain relief at 11 months.3 Base on this clinical data, we believe in offering stem cell therapy to minimize the need for surgical intervention in Osteoarthritic patients. 



Several studies have demonstrated that stem cells can improve functional recovery after a stroke in rats. This recovery occurs when the MSCs are delivered by IV infusion 24 hours post-stroke.4 In addition, delayed delivery of stem cells, even up until one month post-stroke, can also improve long-term functional outcome.5 Multiple studies are making the association with improved motor function, improved memory, neural cell replacement, & anti-inflammatory effects. Mesenchymal Stem Cells have been shown to be still effective when administered 1 week after Traumatic Brain Injury.6 


We believe that in a traumatic event such as a stroke, the patient should have the option of obtaining their cells from our FDA registered stem cell bank to be used within 24 hours of the injury. Based on the studies referenced, it appears using your stem cells can significantly impact recovery and possibly save thousands in hospital, rehabilitation, and unemployment costs. 


Four major studies on Mesenchymal Stem Cells and wound healing show histological findings with enhanced wound healing compared to control treatment. This can be beneficial for millions of individuals suffering from chronic ulcers and wounds.7 


In recent case studies, stem cells showed good therapeutic potential for treatment of Multiple Sclerosis with Lyme Disease. Improvement in walking ability, muscle strength, balance, fatigue, and MRI imaging were all noted within this study. Stem cells show promising results in the treatment of Lyme Disease and Multiple Sclerosis combined with a comprehensive approach to natural medicine.8 

Our network has anecdotal and experimental evidence that stem cell therapy can be effective in healing and regeneration. Stem cells look for damaged tissues, which naturally heal the body. In an effort to provide symptom relief for patients suffering from certain degenerative diseases that are not improving from common modalities of treatment, our network has launched investigational studies of treatment effectiveness with adipose stem cell harvesting. This technological breakthrough allows patients to safely receive millions of their own autologous stem cells. If parents are banking their children’s umbilical cord stem cells for the future, we believe that adults should also have access and take advantage of banking their own stem cells. All of our sterile procedures are non-invasive and done under local anesthesia. Regenerative Medicine LA in collaboration with The Cell Surgical Network is proud to be a world-class facility offering Stem Cell treatment for patients looking for cutting edge therapies to improve their lives. 


1. J, Pak. Regeneration of Cartilage in Human Knee Osteoarthritis with Autologous Adipose Tissue-Derived Stem Cells and Autologous Extracellular Matrix. Biores Open Access. 2016; 5(1): 192–200. 

2. J, Freitag. Mesenchymal stem cell therapy in the treatment of osteoarthritis: reparative pathways, safety and efficacy – a review. BMC Musculoskelet Disord. 2016; 17: 230. 

3. Centeno CJ, Schultz JR, Cheever M, Robinson B, Freeman M, Marasco W. Safety and complications reporting on the re-implantation of culture-expanded mesenchymal stem cells using autologous platelet lysate technique. 

Curr Stem Cell Res Ther. 2010 Mar; 5(1):81-93. 

4. Chen J, Li Y, Wang L, et al. Therapeutic benefit of intravenous administration of 

bone marrow stromal cells after cerebral ischemia in rats. Stroke 2001;32(4):1005-11. 

5. Shen LH, Li Y, Chen J, et al. Therapeutic benefit of bone marrow stromal cells 

administered 1 month after stroke. J Cereb Blood Flow Metab 2007;27(1):6-13. 

6. Mahmood. A Long-Lasting Benefits after Treatment of Traumatic Brain Injury (TBI) in Rats with Combination Therapy of Marrow Stromal Cells (MSCs) and Simvastatin. Journal of Neurotrauma. 2008 Dec; 25(12): 1441–1447. 

7. Isakson, M. Mesenchymal Stem Cells and Cutaneous Wound Healing: Current Evidence and Future Potential. 

8. S, Geeta. Transplantation of Human Embryonic Stem Cells in Patients with Multiple Sclerosis and Lyme Disease. The American Journal Of Case Reports. 2016; 17; 944-949.

Location
Regenerative Medicine LA
9201 Sunset Boulevard, Ste 414
West Hollywood

Los Angeles, CA 90069
Phone: 855-437-7836
Fax: (800) 983-4902
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855-437-7836